Creating a World Without Rett Syndrome

Rett doesn't stop. Neither do we.

The International Rett Syndrome Foundation (IRSF) is laser-focused on creating a world without Rett syndrome. For nearly 40 years, we have fueled life-changing advancements in research toward a cure.

As we relentlessly pursue the best research and breakthrough discoveries in Rett syndrome, IRSF helps families thrive through resources, advocacy, and empowerment.

Our Approach

Transforming the lives of those with Rett syndrome today and tomorrow

Rett syndrome is an incredibly complex disorder that will require a multi-pronged approach to treat and cure. Our unwavering strategy focuses on treatment medications, gene therapy and neuro-habilitative therapies, and we are bringing the first and only treatment that addresses the underlying biology for Rett syndrome into the final phase of clinical testing.