All in at every level
Much goes in to creating treatments and cures for Rett syndrome. IRSF’s investments have already produced game-changing discoveries and built essential treatment development infrastructure. Our leadership and support direct Rett research along a path to treatment and cures for all individuals with Rett.
IRSF’s Scientific Strategy consists of three guiding pillars that cover Rett research at every level:
Critical research– Critical research addresses gaps in researchers’ knowledge of Rett syndrome, including MECP2 and other targets that give rise to the pathology of Rett. It equips researchers with the information they need to devise new ways to treat Rett and improve upon existing ones.
Pipeline development– The Rett treatment development pipeline represents the assessments potential new treatments undergo to prepare for testing in clinical trials. IRSF works to improve the pipeline while helping companies developing Rett treatments to navigate it.
Clinical trials– IRSF supports Rett clinical trials through facilitating communication and connection among the clinical trial stakeholders: Rett families, physicians, the FDA, and trial sponsors. At the same time, it invests in the infrastructure necessary for successful clinical trials such as Rett registries and research onoutcomes measures.
Check out our latest funded research aimed at providing life-changing treatments and a cure.
Rett Syndrome Registry
Learn how IRSF is helping to increase clinical trial success to bring curative treatment options to families.
Rett Research Ready
Find a clinical trial or study and learn how you can become a partner in research.
Center of Excellence Network
Learn how we're advancing best-in-class care and accelerating research.
The Steven G. Kaminsky Scout Program accelerates research by testing new and repurposed compounds for potential use in Rett syndrome.
Natural History Study
The Natural History Study is the most comprehensive study of Rett syndrome in the world.