Ways to Give
IRSF transforms the lives of everyone affected by Rett syndrome through trailblazing research, impactful family support, and bold advocacy initiatives. Invest in the best opportunity to improve the lives of every individual living with Rett.

Give to Create a World Without Rett Syndrome
IRSF is the leading research, family support, and advocacy organization for Rett syndrome. When you donate to IRSF, you not only support trailblazing research, but you also help build awareness of this rare disorder and empower families with the tools to cope with a diagnosis and hope for the future. Thank you for your support!
Why Support IRSF?
Simply put, we know what families need and how to deliver it.
Founded by Rett Families
We were founded by Rett families more than 40 years ago and are proud to continue that legacy today: more than half of our staff and board members are parents, grandparents, or caregivers to an individual with Rett.
Advised by Rett Experts
We are advised by the leading research and clinical Rett experts in the world, experts with the experience to successfully take Rett research from bench to bedside.
Trusted by Industry Partners
We have established relationships with companies working to deliver treatments. They come to us for guidance navigating the Rett landscape to ensure clinical trial success.
The next wave of breakthroughs will only be made possible with your support. Your tax-deductible gift gets us that much closer to a world without Rett syndrome.
Other Ways to Support Our Mission
There are many ways to make a difference in the lives of those living with Rett syndrome. Please consider one of the following:
Donate Stock
Donating appreciated securities is a great way to support our mission while enjoying extra tax benefits. Thank you for considering a gift of stock to the International Rett Syndrome Foundation (dba Rettsyndrome.org). DTC (wire) transfer. If you need additional assistance, please contact our Administrative Director, Brittney Gibson.

Please call and notify our Account Representative of incoming transfer of stock.
Account Representative
Mr. Gordon Warner
Summit Brokerage Services Inc
513-651-5601
gwarner@summitbrokerage.com
Account Information
Corporate name: International Rett Syndrome Foundation
Federal I.D. Number: IRSF: 31-1682518
Account Number: HPH790500
DTC Participant Number: 0443

Please notify Brittney Gibson via email bgibson@rettsyndrome.org or phone at 513-494-8103 once you have completed your transfer.
Corporate Giving
If you are an officer of a corporation, own a family business, or represent a private foundation, there are many options for you to consider for your charitable giving.
If you’re interested in partnering with International Rett Syndrome Foundation by providing support through a corporate or foundation grant, please contact 1-800-818-7388 or admin@rettsyndrome.org.
If you’re interested in becoming an event sponsor at the national or local level, please email events@rettsyndrome.org.
Donate Your Car
Donate your vehicle to the International Rett Syndrome Foundation through our partnership with CARS and support our work with Rett syndrome. CARS will work with you to arrange pick up for your vehicle at no cost to you and most vehicles can be picked up within 24-72 business hours. You’ll receive an initial car donation receipt upon pick-up and then the CARS team will work to turn your car into cash to support our Foundation. Once your vehicle is sold, CARS will provide you proper tax forms in time to file. To donate your vehicle or learn more, please click here.
Employer Match
Did you know that thousands of companies match employee donations to our organization? These matching gift programs help us raise funds to fuel treatments including cures for those living with Rett syndrome.
Please use the below search tool to see if your company will match your donation and if so, get access to the forms, guidelines, and instructions that you need to submit a matching gift.
Estate Planning
Including International Rett Syndrome Foundation in your estate planning can provide tax benefits to you and your loved ones, while helping us work on behalf of those touched by Rett syndrome.
Below is the official designation for including us in your will, trust, life insurance, retirement plan, or other planned gift:
IRSF is a 501(c)(3) non-profit corporation registered as the International Rett Syndrome Foundation (federal tax identification number 31-1682518). Its principal office is located at 4500 Cooper Road, Suite 204, Cincinnati, OH 45242
For more information about supporting IRSF through an estate gift, please contact 1-800-818-7388 or admin@rettsyndrome.org.
Special Programs & Funds
Give to where your gift is needed most or designate a specific fund.
Looking for more ways to make a difference?
There are many ways to join the fight against Rett syndrome. You can raise awareness, get involved in grassroots advocacy, or explore other impactful opportunities. Every action matters. Together, we can transform the lives of those living with Rett.